Software

We’re committed to free and open source software. Primarily, we use Python/Arduino/C to develop solutions to our experimental and analysis problems. Interested in collaborating? Please, get in touch!

HARP

Hierarchical Atomic Resolution Perception (HARP) is software for assessing cryoEM model quality.

• Read the preprint: Scale-dependent hierarchical resolution: applications to atomic resolution and model validation in cryoEM
• Visit the HARP website
• See the code on GitHub

tMAVEN

time-series Modeling, Analysis, and Visualization ENvironment (tMAVEN) is software for post-processing, modeling, and generating publication quality figures for smFRET data. It was made in collaboration with the Gonzalez lab.

• Read the preprint: Increasing the accuracy of single-molecule data analysis using tMAVEN
• Visit the tMAVEN website
• See the code on GitHub

BIASD

Bayesian Inference for the Analysis of Sub-temporal-resolution Data (BIASD) is a method to temporally resolve the kinetics a single-molecule time series, even if those kintics are orders of magnitude faster than the time resolution of the technique.

• Read the first paper: Increasing the Time Resolution of Single-Molecule Experiments with Bayesian Inference
• Read the next paper: Entropic control of the free-energy landscape of an archetypal biomolecular machine
• See the code on GitHub

vbscope

vbscope is archived software from the Gonzalez lab. for analyzing single-molecule localization microscopy data.

• See the code on GitHub